Allergy and Clinical Immunology

Pollen Food Syndrome, in particular Oral Allergy Syndrome (OAS) has been increasing in adults. As it is often difficult to assess the risk for anaphylaxis, a number of these patients are prescribed adrenaline autoinjectors for oral allergy syndrome to peanut and tree nuts with the associated anxiety of carrying an adrenaline autoinjector. Molecular component testing has revolutionized the management of these patients. Patients with symptoms of OAS who have been prescribed an adrenaline autoinjector because of throat tightness and features of anxiety, who have PR-10 / Bet v 1 proteins only and have a safe single blind food challenge and have their adrenaline autoinjectors removed with reassurance that they are not at risk of anaphylaxis, with significant improvement in their quality of life. The talk will present patients from my practice that have had their adrenaline removed following molecular allergy testing and oral challenges, and also patients with less striking history of nut reaction, but molecular testing has identified storage protein sensitization and the risk for anaphylaxis confirmed from this and

adrenaline prescribed based on these tests.