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13th International Conference on Allergy and Clinical Immunology, will be organized around the theme “Emerging Therapeutics for Allergy and Immune Disorders”
Allergy 2018 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Allergy 2018
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Clinical immunology is the branch of immunology which deals with the study of diseases caused due to the disorders in the immune system. The disorders may be failure or aberrant action of immune system and sometimes due to malignant growth of cellular and molecular components of immune system. Hence cellular biology, molecular biology fields of science come into picture. Immunology deals with the study of several components of immune system, the immune reactions and mechanisms. Clinical immunology and allergy is a specialty of renewed interest and untapped potential. It covers several fields like pathology, biochemistry, biotechnology, genetics, pharmaceuticals, medicine etc. The study of these fields give hope to research and taps career for immunologists, cell biologists, molecular biologists, biochemists, bioinformaticians, allergists, physicians, microbiologists, pediatricians and so on. Allergy is the condition of adverse reaction of immune system towards any foreign substance. Allergy is of different types depending on the allergen (causative agent) and the diagnosis and treatment for each type varies.
The invasion of foreign organism on a host body for its growth and multiplication is termed as infection. The infection can lead to infectious diseases/ transmissible disease/ communicable disease. The infection can be caused by any infectious agents and their toxins causing several immune reactions like allergy, inflammation etc. Immune or allergic reactions arise upon infection due to the role of Host immune system to maintain immunity in the body. The infectious agents may be bacteria, virus, fungus, parasites, protozoans etc. As the agents vary, so does the route of transmission to enter into the host body and also the diseases, diagnosis and treatments. The immunity of an individual must be well enough to combat such infections. Immunity will be innately present in an individual from the mother through placenta and also later on through breast milk. Immunity will also be acquired by an individual during his/her lifetime through exposure to several allergens, microorganisms and foreign substances.
- Track 2-1Infectious agents and route of transmission
- Track 2-2Infectious diseases: diagnosis & treatment
- Track 2-3Innate & Acquired immunity
- Track 2-4Autoimmunity & Alloimmunity
- Track 2-5Immunity against pathogens
- Track 2-6Antigens and Allergens
- Track 2-7Antigen-Antibody Interaction
The branch of biology and medicine which deals with the study of immune system in different organisms is immunology. The study covers the several components of immune system, their production, synthesis, function, pathway mechanism etc.The immune system comprises of several components like lymphoid cells and organs, Haematopoiesis, Immune receptors and co-receptors, Major histocompatibility complex (MHC’s), Antibodies and Cytokines, Transcription factors, Cell adhesion molecules (CAM’s) etc. These components play a vital role individually and in a group in an organism’s life against several infections and pathogens. Immunology field of study is an aggregation of several other fields like biology, cellular biology, biochemistry, nanotechnology, molecular biology, biotechnology, bioinformatics, computer science, sensor technology, pathology etc. The field has widened and progressed in several aspects which can be further discussed under the track.
- Track 3-1Clinical & Cellular immunology
- Track 3-2B cells & T cells
- Track 3-3Immune system
- Track 3-4Ocular immunology & Nasal immunology
- Track 3-5Neuroimmunology & Osteoimmunology
- Track 3-6Immunotoxicology & Immunodermatology
- Track 3-7Immunopathology & Immunooncology
- Track 3-8Eco immunology & Diagnostic immunology
- Track 3-9Computational Immunology
- Track 3-10Antigens & Antibodies
Each immune component has its own mechanism pathways for production and function. Molecular and cellular factors involved in these mechanisms must also be studied to get an insight on the immune system and discover solutions for any immune disorders. Molecular and cellular mechanisms which mediate allergic inflammation involve several multiple mediators, cell type and lymphocytes/ interleukins pathways. Allergy or allergic diseases is caused due to hypersensitivity of immune system in response to the genetics or environmental factors. The allergy is of different types with difference mechanism for each. The symptoms range from Rhinitis, inflammation, Allergic urticaria, Atopic eczema, Conjunctivitis, Angioedema and Anaphylaxis. The cure for several involves therapies, vaccines, Antihistamines, Decongestants, Moisturizing creams (emollients) and Steroid medication.
- Track 4-1Immunological Mechanisms of Diseases
- Track 4-2Allergic esophagitis
- Track 4-3Atopic and Contact Dermatitis
- Track 4-4Allergic Asthma
- Track 4-5Cellular pathways
Allergy is one of the most adverse immune reaction faced worldwide by people which is next accompanied by inflammation. The set of conditions caused by Hypersensitivity of the immune system in response to any foreign substance is allergy/ allergic diseases. It may arise due to genetic or environmental factors. The causative agents are termed as allergen and they may be food, drug, dust, pollen, animal dander &fur etc. varying for each individual. Mostly allergen immunotherapy is the advanced therapeutics method to treat the allergies. Allergic and Inflammatory Reactions are caused by the immune system but if the reaction becomes adverse then the condition becomes chronic for an individual. The causative agents for such adverse reactions could be genetic, environmental, pathogenic and synthetic compounds. The localised body part which gets red, swollen, hot and painful after an injury or infection is an condition termed as inflammation and it might be due to allergy: Allergic inflammation or due to tumour. Inflammation can be acute or chronic and it consists of different types based on the part of inflammation.
- Track 5-1Dust Allergy & Latex allergy
- Track 5-2Hay fever (allergic rhinitis)
- Track 5-3Eosinophil-Associated Gastrointestinal Disorders
- Track 5-4Allergic Reactions to dust mites, dust particles& household chemicals like dyes, detergents etc
- Track 5-5Allergic Reactions to pathogenic infections like fungus, mould, bacteria, virus, parasite etc.
- Track 5-6Inflammation: Causes, Symptoms & Treatment
- Track 5-7Inflammatory diseases
The condition of swollen, inflamed and extra mucosal lung airways upon infections or exposure to allergen is asthma/ bronchial asthma and the epigenetics of asthma varies accordingly. The disease or disorder caused due to the abnormal action of the immune system targets smaller airways of the lungs (bronchioles) and makes it difficult for the individual to breathe thus preventing the individual from partaking in any exercises and energy activities. Asthma is long term chronic inflammatory disease of the lung airways caused by any specific allergen (Allergic asthma) or any other genetic / environmental factor (Non-Allergic Asthma) involving symptoms like wheezing, coughing, breath shortness and chest tightness. Sprays are suggested to asthma patients, which help in dissolving the mucus in the airways and creating a path for breathing. Research is going in a rapid pace due to increase in the asthma attack cases, mostly in children (Paediatric Asthma). Asthma allergy immunotherapy and several advances in treatment can be discussed in allergy conference like this.
- Track 6-1Asthma: Signs, Symptoms & Causes
- Track 6-2Asthma attacks, diagnosis and treatment
- Track 6-3Common & advanced asthma medications
- Track 6-4Allergy shots
- Track 6-5Animal study cases on asthma
- Track 6-6Asthma & Pregnancy
- Track 6-7Paediatric Asthma
Chronic obstructive pulmonary disease or COPD is a set of chronic inflammatory lung disease. The disease is contributed by Emphysema and chronic bronchitis. Emphysema is the condition in which the alveoli get destroyed and chronic bronchitis is the condition where inflammation of the lining of the bronchial tubes takes place. The main cause for COPD is exposure to irritating gases or particulate matter, mostly cigarette smoke. People who smoke even after having asthma or people who have long term exposure to chemical fumes, vapours and dusts in the workplace, fumes from burning fuel for cooking and heating in poorly ventilated homes are at risk of developing COPD. Rare cause for COPD is genetic disorder: alpha-1-antitrypsin deficiency. COPD symptoms don’t appear initially hence research in COPD diagnosis in enhancing as misdiagnosis can increase the risk of COPD in the person cause heart disease, lung cancer and so on.
- Track 7-1Signs and Symptoms
- Track 7-2Causes
- Track 7-3Diagnosis
- Track 7-4Prevention and Management
- Track 7-5Prognosis and Epidemiology
- Track 7-6COPD pathophysiology and research
- Track 7-7Emphysema and Chronic bronchitis
- Track 7-8Alpha-1-antitrypsin deficiency
- Track 7-9COPD: Risk factors and complications
Immunity of every individual varies hence the immune reaction by a person to specific food or medication will be different in concern with another individual. Drug allergy is the abnormal reaction of the immune system to any medication. Individuals have shown allergy to certain drugs like penicillin, ibuprofen, aspirin and certain antibiotics. In most of the cases the reaction is mild but some are severe leading to shock and life danger. The general symptoms are hives, fever and rash. Employing the substitute medication, antihistamines, bronchodilators are some treatment methods. Food allergy is immune reaction developed by the body in response to specific food and food component. Few Individuals show allergy after consumption of foods like peanuts, fruit, shellfish, eggs, soy or cow's milk due to certain compound in these foods triggering the immune reaction. Several cases of food allergy are seen epigenetically and cause is still unknown. Symptoms include skin rashes, swelling and itching inside the mouth.
- Track 8-1Epidemiology and Mechanism
- Track 8-2Anaphylaxis
- Track 8-3Food allergy vs. Food sensitivities
- Track 8-4Eosinophilic gastroenteritis
- Track 8-5Pharmacogenomics
- Track 8-6Drug & Food allergy : Causes and symptoms
- Track 8-7Drug & Food allergy : Clinical diagnosis and therapy
Skin and Eye are surface barriers of the body. Skin irritations can be seen due to immune system disorders, medications and infections. Any foreign agent can trigger the immune system upon contacting itself with the surface barriers like skin, eye etc. Upon contact or dust, contact allergy and dust allergy can arise in the eye or skin. Hypersensitivity of immune response due to foreign agent aggravating the skin and conjunctiva causes skin allergy (Atopic dermatitis or contact dermatitis) and Eye allergy (Ocular allergy) respectively. Conjunctiva is the sensitive membrane covering the eye and the eyelid and eye allergy or the ocular allergy is also termed as Allergic conjunctivitis as an allergen firstly irritates the conjunctiva. Mostly all the allergies are severe due to the excess production and overreaction of antibodies mainly Immunoglobulin E (IgE).The symptoms and treatment options slightly vary among the two types of allergy. Causes depend on the allergen and they are mostly self-diagnosable.
- Track 9-1Causes & Symptoms
- Track 9-2Prevention & Cure
- Track 9-3Epidemiology
- Track 9-4Ocular & Dermal Immune system
- Track 9-5Allergic Diseases of cornea & conjunctiva
- Track 9-6Urticaria & Angioedema
- Track 9-7Cutaneous Mastocytosis
- Track 9-8Diagnostic Tests for Ocular & Skin Allergy
- Track 9-9Atopic dermatitis(Eczema)
An allergic reaction to proteins found in an animal's skin cells, saliva or urine is veterinary allergy or Allergology. The pet hair, fur or proteins present in a pet's dander, skin flakes, saliva and urine can induce allergic reaction or cause asthma symptoms in some people. There are several case studies on pet allergies. Pet allergy is mostly seen towards cats and dogs as they are the most common pets worldwide. Cat allergy immunotherapy is widely used by cat lovers. Some cases have been seen where allergy reactions are seen to venom, bite and sting of insects and also to proteins found in animal products where the food allergy comes into picture too. The symptoms may vary among individuals ranging from sneezing, Runny or stuffy nose, Facial pain, Coughing, chest tightness, skin rash or hives to shortness of breath and wheezing
- Track 10-1Allergic Reactions to Stinging and Biting Insects
- Track 10-2Allergic Reactions to venom
- Track 10-3Allergic Reactions to animal dander (tiny flakes of skin or hair)
- Track 10-4Allergic Reactions to animal proteins (cow’s milk)
- Track 10-5Allergic Reactions to pet hair and fur
- Track 10-6Cat Allergy
Considering the case of neonates and children where the immune system is not fully functional at birth and still developing later on, the chances of them being susceptible to infections and pathogens is high and response to vaccines is not that effective compared to adults. This could later lead to development of allergy, asthma or other immune disorders hence the care and prevention methods employed is discussed under Neonatal Immunology and Pediatric immunology. Infants receive their innate immunology through their mother either by placenta when they are in the womb or through breast milk. Immunity acquired later on by infants and kids is acquired through life. Asthma pregnancy i.e. if the mother has asthma then chances exists for children to develop allergy/ asthma. Children who get in contact with several foreign agents are prone to Pediatric Allergy.
- Track 11-1Foetal & Neonatal Immunology
- Track 11-2Paediatric Allergy
- Track 11-3Outdoor & Indoor Allergens
- Track 11-4Paediatric Asthma and Rhinitis
- Track 11-5Vaccination effectiveness
Disorders caused by the deficiency, failure or aberrant action of immune system or the malignant tumour growth in the immune system are immune disorders. They are several type’s namely immunodeficiency disorders (primary and secondary), Allergies and Autoimmune diseases. They are caused by agents like Foods, Latex, Medications, Allergens, Genetics, Pathogenic infections, Stress, Environmental factors and Toxins interacting with proteins. Allergy and inflammatory diseases are immune disorders caused by over reaction of the immune system. The diagnosis, prevention and treatment methods for all varies widening the research in medicine and immunology fields. So far the causes and treatment of several of these disorders is not discovered.
- Track 12-1Allergy
- Track 12-2Hypersensitivity
- Track 12-3Primary Immunodeficiency disorders
- Track 12-4Secondary Immunodeficiency disorders
- Track 12-5AIDS
- Track 12-6Inflammatory diseases
- Track 12-7Complement deficiency disorder
Diagnostic immunology or immunodiagnostics are diagnosis methods and techniques employed for the detection of allergy, asthma and immune disorders like AIDS, Rheumatoid arthritis, Multiple sclerosis, Type 1 diabetes mellitus etc. Allergy diagnosis is segmented into assay kits, instruments and services. Immunoassays, Immunofluorescence, Immunofixation and Immunoadsorption are some of the assays. Instruments involve cytometer, immunoassay analyzers, luminometers, ELISA analyzers, MHC multimer and other instruments. Histology and Immunology tests, molecular methods and immune system assessment are also several other diagnostic techniques.
- Track 13-1Immunoassays & Immunofluorescence
- Track 13-2Neutrophil Function Assessment
- Track 13-3Functional Immune Response Assessment
- Track 13-4Hybridoma technology
- Track 13-5MHC multimer
- Track 13-6Experiments in immunology
- Track 13-7Adoptive cell transfer
- Track 13-8 Histology & Molecular Methods
- Track 13-9Flow cytometry& Mass cytometry
- Track 13-10Immunofixation & Immunoadsorption
- Track 13-11Human Allergic Diseases Assessment
Best way to prevent an allergy is allergen avoidance. Several food allergens like peanuts, seafood, milk, egg, and soybean can be avoided. Drug allergens, dust and pet animals can also be avoided to be allergic free. Other prevention methods involve exclusive breast feeding for 1st 4 months of life, inclusion of Vitamin C, Vitamin E, Omega-3 polyunsaturated oils and good probiotic bacteria in diet, use of Leukotriene receptor antagonists, steroid sprays, Decongestants etc. Vaccination, Immunotherapy and transplantation are now the widely used approaches towards allergy and immune disorders therapy. Gene therapy is the advanced therapeutic approach to fight allergy and immune disorders.
- Track 14-1Allergy therapies and treatment methods
- Track 14-2Immunoglobulin Therapy: Replacement and Immunomodulation
- Track 14-3Glucocorticoids, Vaccines & Antihistamines
- Track 14-4Protein Kinase Antagonists
- Track 14-5Biological Modifiers of Inflammation
- Track 14-6Immunotherapy & Immunization
- Track 14-7Artificial immunity induction
- Track 14-8Organ transplantation
Immunotherapy is one of the preventive treatment method employed against allergy and other immune disorders like asthma, rhinitis, cancer etc. The method involves several types depending on the causes and action for example either the method can prompt the immune system or just provide components and support the immune system. Immunotherapy used to treat cancer is cancer immunotherapy, to treat allergy is allergy immunotherapy, to treat allergic asthma is Asthma allergy immunotherapy, to treat food allergy is food allergy immunotherapy, to treat peanut allergy is peanut allergy immunotherapy. It can be activated, suppressed, helminthic, subcutaneous, sublingual and adjuvant immunotherapy.
- Track 15-1Activation Immunotherapy
- Track 15-2Tumour immunotherapy
- Track 15-3Stem cells based immunotherapy
- Track 15-4Autologous immune enhancement therapy
- Track 15-5Allergen immunotherapy (Desensitisation)
- Track 15-6Sublingual immunotherapy
- Track 15-7Subcutaneous immunotherapy (Allergy shots)
- Track 15-8Allergy immunotherapy
- Track 15-9Helminthic Immunotherapy
- Track 15-10Suppression Immunotherapy
- Track 15-11Others
The engraftment or transfer of cells, tissues or organs for the revival of body functions is transplantation and the process involves several types like Allograft, Xenograft etc. Several ethics and regulations are concerned with the process and as the number of allergy cases has increased after the transplant (Transplant-acquired allergy: TAA) the process is debated and researched for better solutions and reduced/nil allergic and immune reactions. Autologous hematopoetic stem cell transplantation (HSCT) has been used for treatment of severe immune diseases. Transplant surgery success rate is not a huge number with transplant complications and posttranplantation care but it still counts as an effort for the treatment of allergy and immune disorders.
- Track 16-1Transplant-acquired allergy (TAA)
- Track 16-2Autograft
- Track 16-3Allograft
- Track 16-4Xenograft
- Track 16-5Isograft
- Track 16-6Synthetic/ Metal implants
- Track 16-7Transplant rejection and treatment
- Track 16-8Laws and Regulation
- Track 16-9Risks associated with transplant
Biotechnologists made genetically modified crops and organisms to combat world hunger issues however a pause in their production was seen due to several allergy cases & immunological effects. Debate still continues whether the GMO’s trigger allergy? Scientists say no but the main concern arises for food allergy cases as the GM soybean case showed it to be potentially allergic. In-vitro, in silico and digestion tests are performed before the market produce if GMO’s. Considering the immunology, biotechnology specialists later came up with gene therapy, vaccination, Hybridoma technology, Micro Array technology and so on helping out immunologists with diagnosis and therapy of several immune disorders. Gene therapy will be a huge breakthrough for allergy treatment replacing several expensive short term treatments which work out only for some cases.
- Track 17-1Genetically modified organisms (GMO’s)
- Track 17-2Case study of GMO’s allergies
- Track 17-3Vaccination
- Track 17-4Gene Therapy
- Track 17-5Hybridoma technology
- Track 17-6Micro Array technology
Allergy diagnostics and immunotherapeutic market is expected to increase by a huge amount suspects several market analysts due to increasing prevalence of allergic conditions. The increasing lifestyle habits, pollution and urbanization targets diseases like asthma and food allergy at a hype increasing the incidences of allergies and demanding cost effective , sensitive and accurate diagnostic products and therapeutics among hospitals, diagnostic labs and healthcare companies worldwide. The rising level of environmental pollution and the need for faster, accurate and high throughput technologies has increased the allergy diagnostics market product wise with assay kits, immunoassay analyzers, luminometers and ELISA analysers dominating the market which is followed by inhaled allergens. North America followed by Europe, Asia and Middle East are countries accounting for allergy research and market share.
- Track 18-1Antihistamines
- Track 18-2Vaccines
- Track 18-3Allergen products
- Track 18-4Immunotherapy products
- Track 18-5SLIT drops and tablets
- Track 18-6Pollinex Quattro®
- Track 18-7Market sales by country & products