Heri Sutanto
Universitas Brawijaya, Indonesia
Title: Correlation between leukopenia and hospital length of stay in dengue infection
Biography
Biography: Heri Sutanto
Abstract
Dengue infection is a disease caused by dengue virus. Dengue infection sometimes requires hospital admission and even intensive care observation. There is evidence of dengue virus replication in bone marrow leukocytes. Low leukocyte level is associated with more complicated dengue infection. The aim of this study is to determine the relationship between leukocyte levels and Length of Stay (LOS) in patients with dengue infection. This research was conducted at Marsudi Waluyo Singosari Hospital. Data was taken from medical records through 2016-2019, with 201 patients who met WHO clinical criteria for dengue infection. The effect of leukopenia on hospital length of stay, platelet counts and hematocrit levels of the patients was analyzed by the Mann-Whitney method. There was correlation between leukopenia and length of stay (p≤0.001) on patients with dengue infection but not related to platelet counts (p=0.350) and hematocrit levels (p=0.467). The correlation was LOS (day) =3.051+0.516(Diagnosis) + (-.000011)(Lowest Thrombocyte)+0.793 (Leucopenia)(Diagnosis 1=Dengue Fever, 2=Dengue Hemorraghic Fever), lowest thrombocyte (score), Leucopenia (0 =Leucopenia(-), 1=Leucopenia (+)). Leukopenia correlated hospital length of stay in patients with dengue infection.