Developmental Immunology

The study of factors responsible for the evolution of immune cells and organs in the body of organism is Developmental Immunology.  The ability of body to react to antigens depends on a person's age, antigen type, maternal type and the zone where the antigen is present. Maternal factors also play a major role in the body’s immune response. At birth, immunoglobulin is usually present in maternal IgG. Because IgM, IgD, IgE and IgA cannot cross the placenta, and they are undetectable at birth. During adolescence, the human body undergoes various physical, physiological and immunological changes stimulated and mediated by hormones, of which the most significant in females is estrogen and, in males, is testosterone.

Immune system may be divided into two types:

  • Innate immunity
  • Adaptive immunity

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