Allergy and Clinical Immunology

Immunopathology of COVID 19

Indeed though Corona contagion has responsive stimulants for ACE2- expressing epithelial cells of the respiratory tract, systemic hyper inflammation is the severe symptom in cases with COVID- 19. Systemic inflammation causes vasodilation, and allows seditious lymphocytic and monocytic infiltration of the lung and the heart. In particular, pathogenic GM- CSF- concealing T- cells were shown to correspond with the employment of seditious IL-6-secreting monocytes and severe lung pathology in COVID- 19 cases. Infiltrates of lymphocytes have also been reported at necropsy. Organs are substantially affected by a seditious response in cases with murderous COVID- 19.